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Early symptomatic improvement after ustekinumab therapy in patients with ulcerative colitis: 16-Week data From the UNIFI Trial

doi: 10.1016/j.bcp.2025.117293 196 ZhouY.YangZ.ZhuangH.ChenT.KoayS

Methods Materials Diamide, dithiothreitol (DTT), ethylenediaminetetraacetic acid (EDTA), GSH, GSSG, and yeast GR were from Sigma-Aldrich, l-cysteine was from Carl Roth, isopropyl--d-1-thiogalactopyranoside was from Serva, methyl ether poly(ethylene glycol) 24 maleimide (mmPEG) was from Iris Biotech, and NADPH was from Gerbu

The findings suggest that the combination of B12 supplementation and antidepressants significantly enhances symptom improvement in this patient population (329)