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PAS is actively collaborating with researchers to investigate the metabolic reasons as to why some patients need shorter intervals between doses (e.g., monthly or every six weeks and in some instances even more frequently) to maintain their quality of life

Most patients benefit from weekly B12 shots initially, then transition to bi-weekly or monthly maintenance based on their response and lab values

[1] If you experience persistent or concerning symptoms after starting B12 supplements, particularly skin changes or gastrointestinal issues, it is advisable to discuss these with your GP rather than assuming they are directly caused by vitamin excess

Supplementation with B12 may be advised for these groups, and it can be administered orally, through fortified foods, or by injection in cases where absorption may be impaired