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Vitamin C trgt zum Schutz der Zellen vor oxidativem Stress bei

The small molecule drug CA-074-methyl ester reduces lipid peroxidation and mitochondrial dysfunction in macrophages by inhibiting cathepsin B, thereby alleviating ferroptosis and inducing polarization of M2 macrophages, promoting the recovery of nerve function in mice after SCI

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Perfusion was performed by flushing pre-warmed RPMI containing phenol red and L-glutamine through a 25- and 3/8-gauge needle placed into the aorta attached to Tygon tubing aided by the Masterflex L/S perfusion pump as described 81