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No significant acute toxicity was observed in coral-related compound preparations, but if applied for a long time, toxicity to the liver, kidneys, lungs, and other internal organs can still occur in a dose-dependent manner

Archambault L, Vedam S, Starkschall G, Mohan R , Beddar S

However, adenomyosis-derived organoids demonstrated notable differences compared to healthy endometrial organoids, including overexpression of transforming growth factor beta 2 ( TGF2) and SMAD family member 3 ( SMAD3 )