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The latter has a high particle number to mass ratio and unique surface properties, which make them attractive component in many products, although the small size and large surface area potentially make them more toxic than their larger counterparts [8]

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An increase in glyoxalase enzyme activities occurs in plants in response to many different stressors, including osmotic stress, extremes of temperature, heavy metals and exposure to stress-related hormones, including MeJA, ABA and salicylic acid (SA) (Singla-Pareek et al., 2003, 2006

El cido valproico que no logra penetrar utiliza la va de metabolizacin de la sigma oxidacin, cuyo producto, el cido-2-propil-4-pentanoico, inhibe a la enzima carbamoil fosfato sintetasa I (CPS I), que es la primera enzima que metaboliza la urea permitiendo la sntesis de urea en el hgado: captura al amonaco, lo une al bicarbonato y comienza la sntesis de la urea