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When magnesium levels are low, it is common to experience muscle tightness, twitching, or restless legs at night

The anti-folateanti-cancer chemotherapeutic drug methotrexate (Table 1) is used clinically for curing multiple cancers, especially acute leukemia, despite its serious side effects

Some play a role in calming inflammation, which is often tied to memory issues and other cognitive problems

It formally characterises DSIP as a still unresolved riddle acknowledging that no specific DSIP receptor has been confirmed, that the existence of DSIP-like endogenous peptides distinct from DSIP itself may account for a substantial proportion of DSIP-like immunoreactivity data, and that the most robust SWS-promoting activity in rodent studies has been demonstrated for synthetic DSIP structural analogues rather than native DSIP itself