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doi: 10.1016/j.clnu.2010.09.012

Intestinal epithelial barriers Mucosal surfaces that are composed by distinct cell types and separate the internal environment from the external milieu are necessities of maintenance of first-line of defense and body homeostasis

Revised Date: January 18, 2023 Recommendations and Topics Scope Key Recommendations Background Epidemiology Patient Risk Factors Associated with B 12 Deficiency Patient Risk Factors Associated with Folate Deficiency Prevention Diagnosis Management Ongoing Care References Resources Appendix A: Dietary sources of cobalamin Scope This guideline covers the primary care investigation and management of cobalamin (vitamin B 12 or simply B 12 ) and folate deficiency in adults

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