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Apigenin, in turn, promotes TRAIL-induced apoptosis in human RA-FLS and inhibits TRAIL-dependent proliferation of RA-FLS by increasing the expression and activity of caspase-3, decreasing the ratio of Bcl-2/Bax, restoring the expression of cell cycle inhibitors p21 and p27, and activating the PI3K/AKT signaling pathway

Stroke 45 , 25582562 (2014)

Neuronal networks are highly efficient in rapidly altering their structural and functional status, changes that are termed plasticity

A single-center, quadruple-blinded randomized controlled trial evaluating the efficacy and safety of a probiotic formulation consisting of three strains of Lactiplantibacillus plantarum and Pediococcus acidilactici in symptomatic COVID-19 outpatients, showed significantly reduced viral load and lung abnormality scores and increased SARS-CoV-2 specific antibodies (Gutirrez-Castrelln et al., 2022)