Signs of deficiency include: Fatigue and low energy Memory issues and brain fog Numbness or tingling in the hands and feet Mood swings or depression Pale skin and shortness of breath Supplementing Safely: Dosage and Absorption Tips While B12 is generally safe as its water-soluble (meaning excess is excreted), certain considerations can help you get the most out of your supplement: Sublingual Supplements : These are absorbed directly into the bloodstream, bypassing the digestive system, making them ideal for those with absorption issues
A deficiency can lead to fatigue, muscle weakness, and a significant loss of appetite
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This was confirmed to me by my business partner and genius biochemist Nick Andrews, who had the following to say: Chronic administration has been tested and shown to not generate toxic or negative effects while generating the positive effects observed in adipose tissue as well as muscle tissue. My best guess is that this is supported by what has been seen in animal and cell models thus far: 5-amino-1MQ shows in vivo therapeutic efficacy in murine models of DIO (20 mg/kg/d sc.), muscle injury (5 or 10 mg/kg bid
