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(Given the potential long-term consequences of NMOSD relapses, the company could not ethically include a direct placebo arm in its Phase III trial.) Ultomiris was well-tolerated overall, and most treatment-emergent events were mild or moderate in severity, according to AstraZeneca

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Peripheral tinnitus often results from damaged hair cells in the inner ear, while central tinnitus occurs when the brain overcompensates for lost auditory input by creating its own phantom sounds