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HMG CoA is a precursor of cholesterol and is an intermediate that is subsequently converted into -hydroxybutyrate, the primary ketone body in the blood (Figure 24.3.4)

Dec 2009;31(10):655-9

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The usual dose is between 1-3 g per day: Angina and heart failure: 1.5 2 g per day Heart disease: 600 1,200 mg 3 times daily, or 750 mg 2 times daily Peripheral vascular disease: 2 4 g per day Diabetic neuropathy: 3 g per day Male infertility: 300 1,000 mg 3 times daily Chronic fatigue syndrome: 500 1,000 mg 3 4 times per day Overactive thyroid: 2 4 g per day in 2 4 divided doses Shelf Life: This product will retain a 2 year shelf life from the date of manufacturer if properly sealed and stored in a dry, cool environment outside of direct sunlight