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Therefore, there is an unmet need for a novel experimental nerve transection model with small intervening gap that would allow reliable evaluation of the pathophysiology of nerve injury, cellular and molecular mechanisms of nerve regeneration, neural vascularization, muscle atrophy, and functional recovery

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Glossary Amyloid hypothesis proposes that the accumulation of amyloid-beta protein in the brain is the primary cause of Alzheimers disease, leading to the formation of plaques and subsequent neurodegeneration