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23 (5), S70SS3

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Clinically, two independent cohorts confirm relevance: German CAR-T patients with high fecal pentanoate (74.1 g/g) had a 1-year PFS of 90% vs

Preclinical studies in in vitro models have shown that simvastatin exerted its anti-tubercular activity through cholesterol-driven autophagy, which is mediated by the adenosine monophosphate-activated protein kinase (AMPK)mammalian target of the rapamycin complex 1 (mTORC1)TFEB axis [58] (Fig