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doi: 10.3390/ijms21041241 56 DuranteW

Structural comparison with Conformer 1 showed that there is a small but remarkable shift of the entire G i heterotrimer relative to the receptor with a ~15 rotation of the N-terminal -helix (N) and ~10 rotation of the C-terminal -helix (5) of G i in Conformer 2 (Fig