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Scaling up

Gefitinib inhibited the downregulation of ER by EGFR and restored the sensitivity of cells to tamoxifen to a certain extent (Jeong et al., 2019)

Side Effects of NAC NAC is generally well tolerated, but some people experience mild side effects, particularly at higher doses: Nausea or stomach discomfort (the most common complaint, usually resolves after a few days or by taking with food) Diarrhoea at higher doses A sulphurous smell or taste (NAC is a sulphur-containing compound) Rarely, headache or skin rash NAC can interact with certain medications, particularly nitroglycerin (used for angina), where it may enhance the blood-pressure-lowering effect

Foods high in vitamin A include: Dairy products Eggs Fortified cereals Fruits like cantaloupe and pumpkin Vegetables like spinach, broccoli, carrots, and sweet potatoes 3