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Use of certain medications that may interact with B12 or choline metabolism (e.g., metformin, proton pump inhibitors, or anticholinergic drugs)

Consult your doctor before starting or continuing

However, in animals suffered from CSD and received ALA treatment, the activities of both p-Nrf2 and its downstream anti-oxidative enzymes were considerably increased to near the control levels (Figures 3A,C)