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Hypoglycemic activity The amylase inhibition was estimated using the method proposed by Bernfeld, with minor changes 79

Poor attribution skills should also make us skeptical

Similar to rapamycin 31 , these effects were achieved even though not initiated until later in life, which we reasoned to be a safer therapeutic window for IGF-1R modulation than younger ages 34

Disclosures: Ming-Ling Chang: Nothing to Disclose 475 A RARE CASE OF DIFFUSE LARGE B-CELL LYMPHOMA THAT DEVELOPED AFTER SOFOSBUVIR-LEDIPASVIR TREATMENT FOR CHRONIC HEPATITIS C Hiroyasu Sakai 1 Yohei Shirakami 2 Masahito Shimizu 2 , 1 Gifu University Hospital/Department of Gastroenterology, 2 Gifu University Hospital Background: Treatments for chronic hepatitis C virus (HCV) infection have been dramatically improved by the development of direct-acting antiviral agents (DAAs) and almost all patients with HCV can complete antiviral treatment without apparent adverse events