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2) bisubstrate

The more water you drink, the more diluted this pigment becomes which is why well-hydrated urine appears pale yellow, while darker yellow urine can indicate dehydration

[1] Because the cypionate ester markedly increases lipophilicity, the subcutaneous or intramuscular depot undergoes gradual enzymatic hydrolysis, releasing free estradiol that is chemically identical to endogenous estrogen and capable of binding to nuclear estrogen receptors in target tissues

That is, the child will not only improve in words, then articulation, but many parents report that their children notice things that were previously ignored, respond to questions with more understanding and even begin to ask questions spontaneously