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We need some of these radicals because they can act as signaling molecules that trigger important processes (like the heart pumping more blood during stressful moments)

Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: a randomised, open-label phase II trial

Cavallero E, Brites F, Delfly B, Nicolaiew N, Decossin C, Degeitere C, Fruchart JC, Wikinski R, Jacotot B, Castro G

Mechanistically, Notch regulates the expression of METTL3 through the binding of NICD to its downstream transcription factor CSL in the promoter region of METTL3