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Assessment of liver function In assessing the health of the liver, the plasma concentrations of three major biochemical markers: total bilirubin, ALT, and AST were quantified using commercially available diagnostic kits

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After engulfing apoptotic cell debris, macrophages release anti-apoptotic signals and secrete inflammatory factors such as IL-6 and TNF-, which activate survival signaling pathways in DTP cells and promote their survival (86)

Neuroprotection studies in ischemia models, ALS models, and other neurodegenerative contexts have examined IGF-1 and IGF-1 LR3 effects on neuronal survival