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These dioxygenases are required for the differentiation of NSCs derived from embryonic midbrains into dopaminergic neurons, where vitamin C treatment increases 5-hydroxymethylcytosine (5hmC) content and decreases H3k27m3 in promoters of dopaminergic lineage differentiation genes, such as Nurr1 ( 2+ /-KGDDs activated by vitamin C (Wang et al., 2011

10.1016/j.lwt.2024.116083 243 RoversiD.TroianoC.SalnikovE.GiordanoL.RiccitelliF.De ZottiM.et al (2023)

Following the baseline blood draw and ingestion of the capsule of isotope tracer, sequential venous serial blood draws were performed at noted time points for the determination of d 9 -BB metabolites