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Hormone replacement therapy (HRT) is commonly used to alleviate symptoms associated with hormonal insufficiency but remains controversial due to its ability to carries associated risks [22]

DOI: 10.2220/biomedres.37.153

G.GuidaM.CampitielloM

This account traces that arc: the growth hormone-releasing peptide (GHRP) tradition that made ipamorelin conceivable, its characterization at Novo Nordisk in 1998, the 1999 identification of ghrelin that redefined its target, the preclinical program that broadened its research profile, and the clinical and regulatory milestones that followed