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POTS Symptoms can be debilitating and include: Brain fog Severe fatigue and exhaustion Profound weakness with prolonged standing Racing heart Exertional intolerance Muscle aches Lightheadedness Incidence of POTS POTS was estimated to affect between 500,000 and 3 million people in the US before the COVID-19 pandemic

Gray matter images after anatomical standardization were smoothed with a 12-mm isotropic Gaussian kernel at full width at half maximum (FWHM), and a gray matter intensity spectrum was created using the partial volume effect