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Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic

10.1038/s41420-025-02606-6 129 ZhengZ.ShangX.SunK.HouY.ZhangX.XuJ.et al (2024)

The most extensively documented involves upregulation of vascular endothelial growth factor (VEGF) and its receptor VEGFR2, promoting angiogenesis, the formation of new blood vessels, in injured tissue