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GHK-Cu contains minimal copper per dose with copper chelated/bound to the peptide (not free ionic copper), and copper(II) redox activity is silenced when complexed with GHK, allowing delivery of nontoxic copper into the cell

However, further detailed studies must be made in a large number of patients

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This model demonstrates that CEMMs in recycling endosomes maintain the VAMP3STX6 relationship and serve as barriers to restrict VAMP3 activity in autophagic vesicle fusion, whereas CEMM loss promotes autophagosome production and contributes to DOX resistance in breast cancers (128)