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The upper intake limit for calcium is 2,000-2,500 mg daily (age-dependent), with excessive supplementation potentially associated with cardiovascular and kidney stone risks

However, injectable products marketed for human use without FDA approval are considered unapproved new drugs

We also measured total body weight and observed no statistically significant difference between Gdf11 cKO and Gdf11 flox/flox mice in the 6 weeks post tamoxifen treatment (Fig