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Whereas GH insensitivity, both in humans and in transgenic mice, have only mild retardation of growth at birth as previously stated[3135], IGF-I deficiency in gestational state reveals serious postnatal growth retardation, as has been reported both in humans and in transgenic animal models of IGF-I deletion[3640]

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In the present study, CBC regulated the expression of ferroptosis-related genes, including HMOX1 , while simultaneously inducing ROS production and lipid peroxidation

However, even in organs and tissues with low NAMPT expression, NAMPT levels can still be notably high in specific cell types