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The guide cannula was held in place using UV-cured cement (G-bond and G-aenial Universal Flo, GC), and a dummy cannula (PlasticsOne, C315DCS-4/Spc, 2.5 mm) was inserted into the guide cannula to keep the cannulation closed until and in between compound infusions

Although the HFD and MCD models are widely used in NAFLD research, these animal models differ from the pathological processes observed in human NAFLD

It has been demonstrated that LPS-stimulated macrophage membrane-encapsulated nanoparticles (LMNP) have the ability to attenuate CS in HLH