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Therefore, QUE could enhance the cytotoxic effect of 5-FU on HCT116 cells by inhibiting ERK/NLRP3 (36)

Keratinocytes have an immune function against UV by producing cytokines, hormones, chemokines, neuropeptides and antimicrobial peptides (30)

On the other hand, it also shows drawbacks such as: incubation of 20 min is needed, which limits automation, there is no available information about its stability during different times and storage conditions