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To explain these experimental ndings, the corresponding potential energy surface of the S 1 state was constructed as a function of CoC and CoO bond distances, and the manifold of low-lying triplets was plotted as a function of CoC bond length

Firstly, an increasing mRNA expression of various genes associated with an inhibitory effect on cell proliferation was observed, and secondly, a simultaneous increase was seen in the expression of HSD17B2 mRNA, responsible for the conversion of estradiol to its less biologically active formestrone [67,68]

It is clear from these findings that a modification of this assay could easily be applied to human populations to screen for individuals most at risk in noisy environments