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That is far weaker than a Phase 1 human trial

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Its research profile makes it relevant to controlled investigations involving methylation-linked metabolism, energy-balance signaling, metabolic stress response, adipose-associated cellular systems, and cellular adaptation under nutrient-sensitive conditions

Given these potential mechanisms, this study was designed to test the hypothesis that DIO mice restored to the weight and adiposity of LD controls through NNMTi treatment and LD switch 13 have a similar microbiome profile to mice continuously maintained on LD