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Do not use if the vial, ampoule or reconstituted solution shows signs of damage, contamination, particulate matter or discoloration

In contrast, inhibition of NRF2 promotes the maturation of CD80 + and CD86 + DCs (217)

Three patients (11.5%) were able to stop DEX between 17-24 hours, while 6 patients (23.1%) could only discontinue DEX after 24 hours or more following clonidine administration