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To decipher the characteristics of these enhanced autophagic T/ NK cell populations, we re-clustered 7435 T/NK lymphocytes and identified 11 distinct T/NK cell clusters containing cells from AA patients and healthy donors (Figure S2A)

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Morphological characterization of the nanoparticles was performed using a transmission electron microscope (TEM) Hitachi H-7500 operated at 100 kV, and intensity-based hydrodynamic size of the particles (Z-average) in H 2 O was analyzed with Dynamic Light Scattering (DLS) using an Amerigo Particle Size & Zeta Potential Analyzer (Cordouan Technologies, Pessac-Bordeaux, France)