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FRCs from the spleen or lymph nodes were isolated by enzymatic digestion as described previously 55

Taken together, these results suggested that redox control pathways in subcellular compartments are separately and precisely controlled to meet the specific redox requirements in these distinct locations.

Glutamate-cysteine ligase protects cells from ferroptosis by decreasing glutamate levels, converting them to -glutamyl peptides, and boosting GSH production (36) ( Figure 1 )