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VEGF - Vascular Endothelial Growth Factor Skin Structure of the skin The skin covering our body is considered one of the largest organs of our body

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Elevated expression of glutamate/glutamine-associated genes in symbiotic branches corroborates past findings and suggests that with increasing symbiont densities, hosts are more closely regulating nitrogen cycling

Synthesis efficiency depends on age (declining with aging), skin melanin content (darker skin reduces UVB absorption), latitude, and diet (fatty fish, fortified foods, supplements) ( 1.2.2 Vitamin D receptor and its signaling pathways The VDR, a nuclear receptor superfamily member expressed in intestines, kidneys, and immune cells, binds 1,25(OH)2D to regulate gene expression via vitamin D response elements (VDREs)