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(A) The mouse optic nerve head (ONH) labels for microglia (Iba1, white) and astroglia (GFP, red) and cell bodies (blue)

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The viral hijack of human ACE2 receptor disrupts RAAS activation, upregulates NF-B pathway, triggers cytokine storm, hypertension, cell proliferation, inflammation, and fibrosis, where all elicit detrimental effects on every bodily organ during SARS-CoV-2 infection 635