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False negative: the test result is negative, but the person does have the disease

In addition, astrocytic connexin channels, which regulate the transport of adenosine triphosphate (ATP), glutamine and glucose, exhibit altered expression patterns in disease states, shifting astrocytes toward either a neuroprotective or neurotoxic metabolic profile 76

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This study suggests that melatonin pretreatment inhibits radiation-induced apoptosis, and melatonin exerts its radioprotective effect by inhibition of lipid peroxidation and without any involvement of the p53/p21 pathway