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Steadman, J

Methods A multinational and multidisciplinary group of eight practicing experts and opinion leaders in diabetes and endocrinology from various countries across the Gulf region (United Arab Emirates, Oman, Kuwait, Saudi Arabia, and Qatar) convened to establish a consensus group focused on discussing optimal practices for diagnosing and managing PN as a result of its prevalence and challenges in this region

The 5on/2off pattern within the 8-week cycle prevents potential desensitization, and the 8-week off period allows assessment of sustained effects

Then, calcidiol is further converted to the most active form, called calcitriol (1,25-dihydroxyvitamin D), primarily in the kidneys