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Description

Pediatrics 44 PiniL

485 DOX can chelate Fe 3+ to form a complex with Fe 2+ , which triggers excessive lipid peroxidation within mitochondria, resulting in mitochondria-dependent ferroptosis

Very frequently patients do 1-2 cosmetic oriented IV treatments weekly for 8 - 12 weeks

Therefore, regulation of ferroptosis in cardiomyocyte and attenuation of myocardial inflammation in DCM by Nrf2 may provide new therapeutic options for DCM