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Mitochondrial ablation in senescent cells suppressed CCF formation and activates p53, suggesting that mitochondria-dependent formation of H2A.X and CCF dampens nuclear DNA damage signaling and p53 activity in the tissue (Miller et al., 2025)

This unique glutamyl linkage distinguishes glutathione from typical peptides and contributes to its stability against common intracellular peptidases, which is important for both biological function and industrial handling

S.ZaitsevK.LaiL.et al (2022)

Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma