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To determine if GDC inhibits PKA activity directly, GDC solutions were mixed with cAMP and prior to PKA activity measurement

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Burning feet syndrome formally called Grierson-Gopalan syndrome after the physicians who first described it refers to a constellation of symptoms: persistent burning, heat, and sometimes tingling or aching in the feet, characteristically worse at night and partially relieved by cool surfaces or cold water

Our findings were indicated by decreased cardiac TAC and increased MDA in the present study, consistent with previous literature 104,105