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Epidemiological studies conducted on patients suffering from migraine, inflammatory bowel disease, and asthma showed an increased risk of developing the so-called complex regional pain syndrome (CRPS) in the limbs owing to the destruction of nerve fibers [54]

Deciphering the reversible glutaredoxin-dependent redox reactions of roGFP2 therefore not only closes a gap in our knowledge of glutaredoxin catalysis but also facilitates the intrepretation of roGFP2 responses from redox measurements and mechanistic analyses in vivo

In the functional foods and beverages market, its contribution is under 1%, since it is mainly consumed as a supplement rather than integrated into food products

It is the main cause of reversible blindness in the globe today