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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Daas S.I., Rizeq B.R., Nasrallah G.K

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Inhibition of KDM5A increases MPC1 expression in head and neck cancer DTCs, thereby reducing susceptibility to ferroptosis (31).Several drugs targeting the apoptotic pathway in DTCs have already been developed, such as ABT263, a specific inhibitor of the anti-apoptotic proteins BCL-2, BCL-W and BCL-XL, increasing the sensitivity of DTCs to drugs (32)