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An approval statement was granted by the Animal Ethical Committee of the College of Pharmacy/Al-Nahrain University (No.: nah.col.pha.19, date: 24 th October 2022)

This priming-dependent enhanced phosphorylation aligns with our in vivo post-translational modification analysis: S114 phosphorylation is consistently detectable, whereas downstream residues S117 and S120 remain elusive, likely due to the transient nature of their phosphorylation following S114 priming

The altered intracellular redox state has been envisaged as target for anti-influenza therapy, but also in this case the data arising from in vivo studies are inconsistent, and in some cases have indicated that antioxidants could exacerbate the disease

[DOI] [PubMed] [Google Scholar] 67.Schmieden V., Kuhse J., Betz H