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However, a functional assignment of these residues remains difficult because of the absence of structures with transition-state analogues that allow the discrimination between the glutathione moieties from the GSSR substrate or GSH (Fig

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Inhalable nanocatchers for SARS-CoV-2 inhibition

M 2-0-methyl MS 2-0-methyl 3 phosphorothioate cEt //-constrained ethyl(cEt) T -O-methyl 3 thioPACE MSP all of the phosphodiester bonds of a guide are substituted with phosphorothioates (PS) for enhancing levels of gene disruption