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Experts say the unauthorized products fall into regulatory grey zone, with limited evidence of safety and risks that include hormonal imbalances, the growth of cancerous tumours, and liver or kidney damage

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In research contexts, the complex has been explored for its potential to support extracellular matrix maintenance, barrier quality, and tissue remodeling signals, particularly when formulated for topical presentation

While enzymes such as glutathione peroxidase 4 (GPx4) typically utilize cellular glutathione (GSH) stores to scavenge lipid hydroperoxides and prevent LPO-induced damage, erastin-mediated inhibition of cysteine uptake through the Xc- transporter compromises this defense strategy, leading to cell death