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For example, in 2018, Santos et al

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The data indicate that altering the anatomical route and kinetics of nutrient presentation to the distal gut reinstates physiological lipid fluxes and mitigates metabolic dysregulation (7, 49)

These include: Tingling, numbness, or a 'pins and needles' sensation in the hands and feet Difficulty with balance and coordination Muscle weakness Memory problems, difficulty concentrating, or 'brain fog' Mood changes, including low mood or irritability Important: New or worsening neurological symptoms such as paraesthesia, gait disturbance, or cognitive change should be treated as urgent