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AOD-9604 works gradually, producing visible changes over weeks and months rather than days

10.1002/mabi.201900124 67 LiL.XiaoB.MuJ.ZhangY.ZhangC.CaoH.et al (2019b)

Enzymes in the purine salvage pathway, such as adenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT), are essential for Leishmania survival and have been explored as potential targets ( Leishmania has emerged as a promising target