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The hepatoprotective effects of AS-IV involve multiple molecular mechanisms, such as alleviating oxidative stress and inflammatory responses, ameliorating insulin and leptin resistance, inhibiting excessive autophagy and ER stress, suppressing angiogenesis, remodeling the gut microbiota, preventing ferroptosis, and inhibiting HCC cell proliferation, invasion and migration while promoting tumour cell apoptosis

pH measurements resulted in a decrease of pH down to pH \(\approx \) 1 after plasma treatment times of 5 min or longer

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