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It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

Doctors often combine Alimta with cisplatin and carboplatin to increase its effectiveness, extend survival rates and improve quality of life for mesothelioma patients

Patients should be educated on appropriate administration techniques for each

[DOI] [PubMed] [Google Scholar] 115.Eigner W., Bashir K., Primas C., Kazemi-Shirazi L., Wrba F., Trauner M., Vogelsang H